What are artificial sweeteners? What is the role of artificial sweeteners in health and disease?  

Artificial sweeteners are low-calorie or calorie-free sugar substitutes used to sweeten food and drinks. They are often used as a replacement for sugar in order to reduce calorie intake and help manage weight. Artificial sweeteners are many times sweeter than sugar, so smaller amounts can be used to achieve the same level of sweetness. Some of the most commonly _______ _________ ____ __________ _________ ____ _____ ____.
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