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Purine catabolism in humans involves the sequential degradation of adenine and guanine nucleotides to uric acid, and xanthine oxidase plays a central role in the final oxidative steps of this pathway. Purine nucleotides are first converted into their corresponding nucleosides ______ _________ ________ ___ ______ _____ _________ ____ _____ _____ _____ ________.
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