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The oxidation of monoalkylacetylenes using thallium nitrate is a useful method in organic synthesis for converting acetylenic compounds into α-keto carbonyl compounds. In this reaction, a terminal alkyne or monoalkylacetylene undergoes oxidation in the presence of thallium(III) nitrate, which acts as a strong oxidizing agent. The reaction is generally carried out in an ____ ______ ____ __________ _________ _______ __________ ___.
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