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Fischer indole synthesis is an important method for the preparation of indole and substituted indoles from aryl hydrazines and aldehydes or ketones under acidic conditions. In this reaction, an aryl hydrazine first reacts with a carbonyl compound to form a hydrazone. On heating with a strong acid such as hydrochloric acid, sulfuric acid, or polyphosphoric acid, the hydrazone ______ __________ _____ ____ ___ _______ ________ ______.
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