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Edward Jenner, an English physician of the late 18th century, made a pioneering contribution to immunology through the development of the smallpox vaccine, which laid the foundation for modern vaccination. Jenner observed that milkmaids who had contracted cowpox, a mild disease from cows, did not suffer from smallpox, a deadly human disease. __________ _________ ____ ________ _____ __________ _____ ______.
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