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Complement-induced lysis through membrane attack complex (MAC) formation is a crucial part of the innate immune system that targets and destroys pathogens, especially Gram-negative bacteria. The process begins with activation of the complement system through any of the three pathways: classical, lectin, or alternative. All these pathways converge at the cleavage of complement protein C3 _______ ______ ______ ______ ________ __________.
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