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Immunoglobulin M (IgM) is the first class of antibody produced during an initial immune response. It is a pentameric molecule in its secreted form, consisting of five immunoglobulin units linked by a joining (J) chain, which gives it a large size and high valency. Due to this structure, IgM can bind simultaneously to multiple antigens, making it particularly effective ____ ______ ________ ________ ________ ______ _____ _____.
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