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Multiple Sequence Alignment (MSA) is a fundamental method in genomics and proteomics used to align three or more biological sequences—DNA, RNA, or proteins—simultaneously to identify regions of similarity that may indicate functional, structural, or evolutionary relationships. Unlike pairwise alignment, which compares only two sequences, MSA allows researchers to analyze a broader set of sequences to detect conserved motifs, domains, or residues _______ _______ _______ ________ __________.
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