Question

Suppose that there is a mixture having a specific rotation of +75o and an enantiomeric excess of 60%. Find out the enantiomeric composition of the mixture. 

22 Jan 2025
Answer :
Word Count : 341

To calculate the enantiomeric composition of the mixture, we need to use the relationship between the observed specific rotation, enantiomeric excess (ee), and the specific rotation of the pure enantiomer.

The formula to calculate enantiomeric excess (ee) is:

\[
\text{ee} = \frac{[\alpha]_{\text{observed}}}{[\alpha]_{\text{pure}}} \times 100
\]

Where:
- \([\alpha]_{\text{observed}}\) is the observed specific rotation,
- \([\alpha]_{\text{pure}}\) is the specific rotation of the pure enantiomer.

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