What is the principle of microscopic reversibility? Explain taking the example of an addition-elimination reaction or a nucleophilic substitution reaction.

The principle of microscopic reversibility states that the mechanism of a reaction in one direction is the reverse of the mechanism in the opposite direction at the molecular level. It asserts that the pathway taken by the reacting molecules in a forward reaction mirrors the pathway they follow in the reverse reaction, with the same transition states and intermediate species. This principle is fundamental in _____ _______ __________ ___ ____ _____ _________ __________ __________ ______ _____ _____.
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