Question

How are disubstituted cyclohexanes different from monosubstituted cyclohexanes with reference to the isomerism? Draw the two chair conformations for each of the following disubstituted cyclohexanes. Draw also the cis and trans isomers and indicate the more stable isomer.

i) cis-Bromo-1-methylcyclohexane

ii) trans-2-Butyl-1-isopropylcyclohexane

iii) cis-4-Ethyl-1-hydroxycyclohexane

22 Jan 2025
Answer :
Word Count : 294

Disubstituted cyclohexanes exhibit more complex isomerism compared to monosubstituted cyclohexanes due to the additional positions where substituents can be placed. The primary types of isomerism seen in disubstituted cyclohexanes are cis-trans isomerism and chair conformation stability. The cis isomer refers to both substituents being on the same side of ________ ______ _____ __________ _________.
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