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B-cell and T-cell epitopes are distinct regions of antigens that elicit specific immune responses, and their properties are tailored to the mechanisms of recognition by B-cell receptors (BCRs) and T-cell receptors (TCRs). B-cell epitopes are generally accessible regions on the surface of antigens that antibodies can directly bind. These epitopes can be either linear, consisting of a sequential stretch of amino acids, or conformational, formed __________ ________ _________ __________ _________ ________ _______ __________ ________.
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