Question

Give a schematic representation of metabolic reactions in Krebs cycle? Explain its significance?

08 Mar 2025
Answer :
Word Count : 417

Schematic Representation of Metabolic Reactions in Krebs Cycle

The Krebs cycle, also known as the Citric Acid Cycle (CAC) or Tricarboxylic Acid (TCA) Cycle, is a central metabolic pathway occurring in the mitochondrial matrix. It plays a crucial role in cellular respiration by oxidizing acetyl-CoA into carbon dioxide (CO₂) while generating high-energy electron carriers (NADH and FADH₂) and ATP. The cycle consists of a series of enzymatic reactions, which can be schematically represented as follows:

Schematic Diagram of the Krebs Cycle

  1. Acetyl-CoA (2C) + Oxaloacetate (4C) → Citrate (6C)

    • Enzyme: Citrate Synthase
    • Acetyl-CoA combines with oxaloacetate to form citrate.
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