Purine catabolism

Question

Purine catabolism

08 Mar 2025

Answer :

Word Count : 423

Purine catabolism refers to the breakdown of purine nucleotides (adenine and guanine) into their end products, which vary among different organisms. This process is essential for maintaining nucleotide balance, recycling purine bases, and eliminating excess nitrogenous waste.

### Key Steps in Purine Catabolism:

1. Conversion of Nucleotides to Nucleosides:
- Purine nucleotides (AMP and GMP) are first dephosphorylated by nucleotidases, producing adenosine and guanosine, respectively.
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