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The Renin-Angiotensin-Aldosterone System (RAAS) is a crucial hormonal cascade in vertebrates that regulates blood pressure, fluid balance, and electrolyte homeostasis. It is primarily activated in response to low blood volume, low blood pressure, or decreased sodium concentration in the distal tubules of the kidney. The system begins with the release of renin, an enzyme secreted by the juxtaglomerular cells of the kidney __________ _____ __________ ______ _________ _______.
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