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Enzymes are biological catalysts that accelerate chemical reactions in living organisms by lowering the activation energy required for the reaction to proceed. Activation energy is the minimum energy needed for reactants to reach the transition state and form products. Enzymes achieve this by stabilizing the transition state, bringing substrates into close proximity, and providing an optimal microenvironment for the reaction. One key mechanism through which ________ ______ _________ ______ ________ ______ ______.
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