Explain any two vectors used for cloning large DNA fragments.

Question

21 Dec 2024

Answer :

Word Count : 269

Recombinant DNA technology involves the use of vectors to introduce foreign DNA into host cells for replication and expression. Two commonly used vectors for cloning large DNA fragments are bacterial artificial chromosomes (BACs) and yeast artificial chromosomes (YACs).

Bacterial Artificial Chromosomes (BACs) are based on the F-plasmid of *Escherichia coli*. They are designed to carry large fragments of foreign DNA, typically between 100 to 300 kilobases (kb). _____ _______ ________ _________ ________ ______ _______ ____.
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