Question

Discuss the role of phase transfer catalysis in nucleophilic substitution reactions.

21 Jan 2026
Answer :
Word Count : 268
Phase transfer catalysis plays a significant role in facilitating nucleophilic substitution reactions by enabling the interaction between reactants present in different, immiscible phases, typically an aqueous phase and an organic phase. Many nucleophiles such as hydroxide, cyanide, halide, or sulfide ions are generated in aqueous media, while organic substrates like alkyl halides or sulfonates are soluble only in organic solvents. In the absence of a phase transfer ______ ____ ___ ______ ___ ___ _________ _______.
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