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Proteins are essential biomolecules that perform a wide variety of functions in living organisms, including catalyzing biochemical reactions, providing structural support, transporting molecules, and regulating cellular processes. For proteins to function properly, they must fold into specific three-dimensional shapes dictated by their amino acid sequences. Protein folding is a highly regulated process, and any disruption in this process can lead to misfolding, resulting in proteins that are non-functional or toxic to cells. Protein mis-folding diseases are a group of disorders caused by the accumulation of these abnormally folded proteins, which often _________ _______ _______ ________ ___ ______ _____ ________ __________ ____.
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