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Superantigens are a unique class of antigens that trigger an unusually strong immune response by directly linking major histocompatibility complex (MHC) class II molecules on antigen-presenting cells to T-cell receptors on T lymphocytes, bypassing the normal antigen processing. Unlike conventional antigens, which activate a very small fraction ______ ____ ____ _____ ____ ______ ________ ___ _______ ______ ____.
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