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Apoferretin is the protein shell of ferritin, which functions as a major iron storage protein in biological systems. It is a hollow, spherical macromolecule with an external diameter of about 120 Å and an internal cavity of nearly 80 Å, designed to store iron in a safe, soluble, and non-toxic form. The shell of apoferretin is built from 24 identical polypeptide subunits that assemble into ___ ________ ___ ___ _____ _________ _________ ____.
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