Question

What is "Apathetic thyrotoxicosis"?

22 Jan 2025
Answer :
Word Count : 517

Apathetic thyrotoxicosis is an atypical presentation of hyperthyroidism, particularly observed in elderly patients, where the classic hypermetabolic and sympathetic overdrive symptoms of the condition are muted or absent. Instead, it manifests with nonspecific and often subtle clinical features, such as apathy, lethargy, depression, and diminished physical activity. This form of thyrotoxicosis poses a diagnostic challenge due to its uncharacteristic presentation, which can easily be mistaken for other conditions commonly seen in geriatrics, such as depression, dementia, or generalized frailty.

### Pathophysiology  
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