Biological in management of Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by persistent joint inflammation, leading to cartilage damage, bone erosion, and progressive disability. The management of RA has evolved significantly with the introduction of biological therapies, particularly in Clinical Geriatrics-II, where considerations for older adults with comorbidities and polypharmacy are critical. Biological agents target specific components of the immune system, providing improved outcomes compared to traditional disease-modifying antirheumatic drugs (DMARDs).
### Mechanism of Action of Biologics
Biological therapies focus on interrupting specific pathways involved in RA pathogenesis. These include:
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