Treatment resistance

Treatment resistance is now recognised across a range of psychiatric disorders, including schizophrenia, major depressive disorder (MDD), bipolar affective disorder , and obsessive compulsive disorder (OCD) . Despite this, treatment resistance was not a focus of psychiatric drug development for decades and, to date, only one treatment, clozapine, is a licensed monotherapy for treatment resistance in psychiatry, and then specifically for schizophrenia. However, there are signs of change, with _____ _____ _________ ________ ____.
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