Question

 PAM and BLOSUM

11 Sep 2025
Answer :
Word Count : 129
FeaturePAM (Point Accepted Mutation)BLOSUM (BLOcks Substitution Matrix)
Full FormPoint Accepted MutationBLOcks Substitution Matrix
Data SourceProtein sequences with known evolutionary relationshipsHighly conserved regions (blocks) of protein families
Matrix ConstructionDerived by calculating the probability of amino acid ________ ________ __________ ________ ___ __________ _______ ________.
____ ____ _________ _________ ________ ______ ___ _______ ________ __________.
_____ _____ ____ _________ _____.
__________ ________ ______ ___ ________ __________ __________ ________ ________ ____ _____ ____.
_______ _______ _____ ______ _________.
______ ______ ______ ____ __________ ____ _____ ________ _________ _________ ____.
_____ _______ _________ ______ ___ _________ _______ ___ ______.
____ ________ ____ __________ ________ ____ ___ _________ ___.
_____ ____ ___ ______ _________ ________ _____ ______ __________ _______ _____.
_________ ___ ________ __________ __________ ______.
________ ________ _____ __________ ___ _____ ____ _________ ______ __________.
____.
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