Word Count : 237

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The Chou-Fasman method predicts β-sheets by using empirically derived conformational parameters for each amino acid. The first step is to assign β-sheet propensity values (Pβ) to every residue in the protein sequence based on statistical frequencies observed in known _____ _________ _______ _____ __________ ____ ____ ________ ______ ____ _______.
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