How following factors influence the immunogenicity?
a) Traits of Host
b) Traits of Immunogen
### a) Traits of Host
1. Genetic Makeup: The host's genetic background, such as Major Histocompatibility Complex (MHC) alleles, influences the ability to present antigens and initiate an immune response.
2. Age: Newborns and the elderly have weaker immune systems, affecting immunogenicity. Newborns may rely on maternal antibodies, while the elderly exhibit immunosenescence.
3. Health Status: Immunocompromised or malnourished hosts exhibit reduced immunogenicity due to weakened ________ ______ ________ _______ _____ _______ ________ _________ _______.
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