Question

How following factors influence the immunogenicity?

a) Traits of Host

b) Traits of Immunogen

23 Jan 2025
Answer :
Word Count : 290

### a) Traits of Host  
1. Genetic Makeup: The host's genetic background, such as Major Histocompatibility Complex (MHC) alleles, influences the ability to present antigens and initiate an immune response.  
2. Age: Newborns and the elderly have weaker immune systems, affecting immunogenicity. Newborns may rely on maternal antibodies, while the elderly exhibit immunosenescence.  
3. Health Status: Immunocompromised or malnourished hosts exhibit reduced immunogenicity due to weakened ________ ______ ________ _______ _____ _______ ________ _________ _______.
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