Holoenzyme

A holoenzyme is an enzyme that consists of both a protein component and a non-protein component. The protein part is called the apoenzyme, and the non-protein component, which is crucial for the enzyme's activity, is often a cofactor or coenzyme. The cofactor or coenzyme can be a metal ion, a vitamin, or a derivative of a ______ ________ _________ ________ ____ _________ _______ _________ ________ __________ ________ ____.
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