Question

Give the etiology and clinical features of the following deficiency diseases:
 i) Ariboflavinosis
 ii) Pellagra

07 Feb 2024
Answer :
Word Count : 666

Deficiency diseases are conditions that arise due to the lack of essential nutrients in the diet. Here, we will discuss the etiology (causes) and clinical features of two such deficiency diseases: ariboflavinosis (riboflavin deficiency) and pellagra (niacin deficiency).

I. Ariboflavinosis (Riboflavin Deficiency):

Etiology: Ariboflavinosis is caused by an inadequate intake or absorption of riboflavin (vitamin B2) in the diet. Riboflavin is a water-soluble vitamin that plays a crucial role in various metabolic processes in the body. The primary causes of riboflavin deficiency include:

  1. Dietary deficiency: A diet lacking in riboflavin-rich foods, such as milk, eggs, meat, green leafy vegetables, and whole grains, can lead to deficiency over time.
  2. Malabsorption: Certain gastrointestinal disorders, such as Crohn's disease, celiac disease, or chronic diarrhea, can impair the absorption of riboflavin from the diet.
  3. Increased requirements: Pregnant and lactating women, as well as individuals with certain medical conditions like hyperthyroidism or chronic kidney disease, may have increased riboflavin requirements.
  4. Alcohol abuse: Chronic alcohol consumption can interfere with the absorption _____ _____ __________ _________ _________ _______ _________ ________ _____.
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