give a general reaction of asymmetric 1, 2-aminohydroxylation of alkenes using (DHQ)2-PHAL AD catalyst in the presence of (TsNCINa). Also give various nitrene equivalents which are frequently as reagents in this reaction.
The asymmetric 1,2-aminohydroxylation of alkenes is an important method for the preparation of vicinal amino alcohols with high enantioselectivity. A general reaction involves the use of a chiral ligand such as (DHQ)₂-PHAL in combination with an oxidant in the presence of nitrene precursors. In the typical protocol, an alkene substrate reacts with a nitrene equivalent like TsN–X (where X _______ ___ __________ ________ ________ ______ __________ __________ _________ ________ ______ _________.
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Describe the uses of benzotrioles.
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) 3-Methylazacyclohexane
Discuss any two methods of preparation of oxetanes giving suitable examples.
Discuss the disconnections for the synthesis of paracetamol. Also write its scheme of synthesis. Draw the general scheme/mechanism of Stille coupling reaction. Give examples of some additives which are used to increase the rate of these reactions.
Discuss the sequence of reactions for preparing the following compound using ethylaceoacetate
