Word Count : 262

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Ion channels are specialized protein structures in the neuronal membrane that allow the selective flow of ions such as sodium (Na⁺), potassium (K⁺), calcium (Ca²⁺), and chloride (Cl⁻), which are essential for generating and propagating nerve impulses. The process of nerve impulse transmission, or action potential, depends on the precise opening and ______ ___ ______ _______ ______ ___ _____ __________ _______ ______ _____.
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