Eicosanoids

Eicosanoids are a group of bioactive lipid molecules that play crucial roles in various physiological and pathophysiological processes. They are primarily derived from polyunsaturated fatty acids, especially arachidonic acid, which is a 20-carbon fatty acid with four double bonds. Arachidonic acid is released from membrane phospholipids by the action of phospholipase A2, and it serves as a precursor for the synthesis of eicosanoids. The two major classes of eicosanoids are prostanoids (including prostaglandins, thromboxanes, and prostacyclins) and leukotrienes. These molecules have profound effects on inflammation, immune response, blood clotting, vascular ______ ______ __________ ___ _____ ___ _____ _________ _______ ___ _________.
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