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Organophosphates (OPs) and carbamates are two major classes of insecticides that primarily act by inhibiting the enzyme acetylcholinesterase (AChE), but they differ significantly in the nature and reversibility of their action. Acetylcholinesterase is responsible for hydrolyzing the neurotransmitter acetylcholine at synapses, thus terminating nerve impulses. Inhibition of this enzyme _____ ________ ________ ____ _________ ___.
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