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Organophosphates (OPs) and carbamates are two major classes of insecticides that primarily act by inhibiting the enzyme acetylcholinesterase (AChE), but they differ significantly in the nature and reversibility of their action. Acetylcholinesterase is responsible for hydrolyzing the neurotransmitter acetylcholine at synapses, thus terminating nerve impulses. Inhibition of this enzyme leads to the accumulation of acetylcholine, resulting in continuous stimulation of cholinergic _________ _____ ________ _______ __________ _____ __________ ______.
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