Describe the pathophysiology of Alzhemir's disease. What is role of amyloid beta plaque and tau protein?

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by memory loss, cognitive decline, and behavioral changes. Its pathophysiology involves a combination of genetic, environmental, and cellular factors that lead to the degeneration of neurons, particularly in the hippocampus and cortex, which are critical for memory and cognitive functions.

One of the hallmark features of Alzheimer's disease is the accumulation of abnormal protein aggregates in the brain. Two key proteins involved in the disease's pathogenesis are amyloid beta (Aβ) and tau protein. These proteins play crucial roles in the progression of the disease, contributing to neuronal dysfunction and death.

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