Describe SDS-PAGE and its significance in characterization of proteins.

SDS-PAGE (Sodium Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis) is a widely used technique in bioanalytical science for separating proteins based on their molecular weight. The principle behind SDS-PAGE lies in the use of sodium dodecyl sulfate (SDS), a detergent that denatures proteins by disrupting their secondary, tertiary, and quaternary structures. SDS __________ ________ _________ _____ _________ __________ __________ _______ _______ ____ ______ ______.
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