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Cyclin-dependent kinases (CDKs) are a family of serine/threonine protein kinases that play a central role in regulating progression through the cell cycle. By themselves, CDKs are catalytically inactive enzymes. Their kinase activity is dependent on binding to regulatory proteins known as cyclins, hence the term cyclin-CDK kinases. ________ ______ __________ __________ ________ ___ ____ _______ __________ ______ ____ _____.
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