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Cofactors are non-protein chemical components that are required for the proper functioning of many enzymes. They assist enzymes in catalyzing biochemical reactions that cannot be carried out by the protein part alone. The enzyme without its cofactor is called an apoenzyme, which is inactive, and when combined with its cofactor it forms an active holoenzyme. Cofactors may be inorganic ions or organic _________ ____ _______ ________ ________ _____ _______ ________ ________ __________ ______.
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