Question
Explain Negishi coupling reaction with an example and give its mechanism.
Answer :
Word Count : 239
Negishi coupling reaction is a powerful cross-coupling reaction in organic chemistry that involves the formation of a carbon-carbon bond between an organozinc compound and an organic halide or pseudohalide in the presence of a palladium or nickel catalyst. This reaction is widely used in the synthesis of complex organic molecules, including pharmaceuticals, natural products, and conjugated systems. The general _______ ________ _____ _________ _____.
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Negishi coupling reaction is a powerful cross-coupling reaction in organic chemistry that involves the formation of a carbon-carbon bond between an organozinc compound and an organic halide or pseudohalide in the presence of a palladium or nickel catalyst. This reaction is widely used in the synthesis of complex organic molecules, including pharmaceuticals, natural products, and conjugated systems. The general _______ ________ _____ _________ _____.
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