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Drugs can be derived from multiple sources, each offering unique chemical entities that can be developed for therapeutic use. The primary sources of drugs include natural, synthetic, and semi-synthetic origins. Natural sources encompass plants, animals, and microorganisms. Plant-derived drugs have historically been significant, with compounds like morphine from *Papaver somniferum* and quinine from *Cinchona* bark being classical examples. Animal sources contribute biologically active substances such as insulin from pancreatic extracts and heparin from porcine intestinal mucosa. Microorganisms, particularly bacteria and fungi, are valuable ________ _____ ____ _______ ______ ________ ___ ________ _________ ______ ________.
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