Write the significance of K., and V, in enzyme activity.

In enzyme activity, the constants K\(_m\) (Michaelis constant) and V\(_m\) (maximum velocity) play a critical role in determining the efficiency and characteristics of an enzyme-catalyzed reaction.

K\(_m\) is a measure of the affinity of an enzyme for its substrate. It is defined as the substrate concentration at which the reaction rate is half of V\(_m\). A low K\(_m\) value indicates a _____ __________ ___ ____ _______ _______ ________ ___ ________ _________ ________ _______.
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