Write the significance of K., and V, in enzyme activity.

In enzyme activity, the constants K\(_m\) (Michaelis constant) and V\(_m\) (maximum velocity) play a critical role in determining the efficiency and characteristics of an enzyme-catalyzed reaction.

K\(_m\) is a measure of the affinity of an enzyme for its substrate. It _____ ______ _____ ________ ___ ________ ___ _________.
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