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Apoferretin is the protein shell of ferritin, which functions in iron storage in biological systems. It is a hollow, roughly spherical protein composed of 24 polypeptide subunits arranged in a highly symmetric manner, forming a shell with an outer diameter of about 12 nm and an inner cavity of 8 nm. The subunits are of two types: H (heavy) chains and L (light) chains, which assemble in _______ ________ ______ ________ _______ ___ ___ _____ _________ ___ _________ ______.
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