What is the factors affecting biotransformation of drugs

Biotransformation, also known as drug metabolism, is the process by which the body alters drugs and other foreign substances to make them more easily excreted. There are several factors that can affect the biotransformation of drugs, including:

1. Genetic factors: Individual genetic differences can affect the activity of drug-metabolizing enzymes, such as cytochrome P450 enzymes, which play a major role in drug biotransformation. Variations in the genes that ______ _______ _________ _________ _______ ___ ____ ______ _____ ____.
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