Discuss briefly the factors affecting bioavailability. 

Bioavailability refers to the extent and rate at which a drug or other substance is absorbed into the systemic circulation and becomes available at the site of action. Several factors can influence the bioavailability of a drug, affecting its absorption, distribution, metabolism, and elimination. Understanding these factors is crucial in optimizing drug formulations and ensuring therapeutic efficacy. Here are some key factors that can affect bioavailability:

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