What is role of inflammation in host defense against a pathogen?

Inflammation plays a crucial role in the body's defense mechanism against pathogens by initiating an immune response that limits the spread of infection and promotes healing. When a pathogen enters the body, it triggers the release of various signaling molecules such as cytokines, chemokines, and prostaglandins. These molecules act as messengers to alert surrounding tissues, ____ _____ ______ __________ ______ ___.
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