What are the factors which affect the efficacy of scientific evidence?

Plant sterols are naturally occurring molecules that humanity has evolved with. Herein, we have critically evaluated recent literature pertaining to the myriad of factors affecting efficacy and safety of plant sterols in free and esterified forms. We conclude that properly solubilized 4-desmetyl plant sterols, in ester or free form, in reasonable doses and in various vehicles including natural _________ ___ ___ ____ _____ ________ _____ ___ __________ _________ _______ ______.
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