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Protein Kinase B (PKB), also known as Akt, is a serine/threonine-specific protein kinase that plays a crucial role in multiple cellular processes, including metabolism, growth, proliferation, survival, and angiogenesis. Biochemically, PKB is activated downstream of phosphoinositide 3-kinase (PI3K) _____ __________ _______ ___ _________ ____ ________.
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