Word Count : 137

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Myxoedema is a clinical condition resulting from severe hypothyroidism, typically due to deficiency of thyroid hormones, mainly thyroxine (T4) and triiodothyronine (T3). Biochemically, the lack of thyroid hormones leads to a reduction in basal ____ _____ ____ _________ ____ _________ _____ ________ _______ _______ ________ ____.
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