Multiple myeloma in elderly
Multiple myeloma, a malignant proliferation of plasma cells, poses significant challenges in elderly patients. As the most common hematologic malignancy in older adults, its prevalence increases with age, with a median age at diagnosis of around 70 years. Clinical management of multiple myeloma in the elderly requires a comprehensive understanding of the disease's unique characteristics, including its clinical presentation, diagnostic approach, treatment options, and considerations for geriatric patients.
Clinical Presentation:
Multiple myeloma often presents with a wide range of clinical manifestations, including bone pain, anemia, renal dysfunction, hypercalcemia, and recurrent infections. However, in elderly patients, these symptoms can be subtle or attributed to age-related comorbidities, leading to delayed diagnosis and advanced disease stage at _____ _______ _____ _________ ____ _______ ____ ___ ________ __________.
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