Medications used in thrombolytic used in acute ischaemic stroke. What is their mechanism of action ?

Thrombolytic therapy plays a crucial role in the management of acute ischemic stroke, a condition characterized by the sudden loss of blood flow to a part of the brain due to a blockage in an artery. The primary goal of thrombolytic therapy is to dissolve the blood clot causing the ischemia and restore blood flow to the affected area of the brain. Two main medications commonly used for thrombolytic therapy in acute ischemic stroke are alteplase (recombinant tissue plasminogen activator, or rt-PA) and tenecteplase.

Mechanism of Action:

1. Alteplase (rt-PA):
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