How is carbon dioxide transported when it is released by the tissues into the blood in mammals? What is the role of carbonic anhydrase?
Carbon dioxide (CO2) is a byproduct of cellular respiration that occurs in the tissues of mammals. The concentration of CO2 in the tissues is higher than that in the blood, so CO2 diffuses from the tissues into the blood. Once in the blood, CO2 is transported in one of three ways: dissolved in plasma, bound to hemoglobin, or converted to bicarbonate ions (HCO3-) via an enzymatic reaction involving carbonic anhydrase.
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